COVID-19: the trials ongoing worldwide | Fonds Anticancer (FR)

COVID-19: the trials ongoing worldwide

We are an organisation focused on cancer treatments and cancer patients, but we couldn't stand on the sidelines in the fight against COVID-19. We used our expertise in research to track down all the clinical trials ongoing in COVID-19 and we produced an overview, easy to access.

Our open-access database

Link to the database:  http://www.redo-project.org/covid19db/
Summary of the data: http://www.redo-project.org/covid19_db-summaries/

By making its database public the Anticancer Fund wants to alert researchers to the wide range of hypotheses being explored around the world. With so many trials being developed in such a short timeframe duplication of effort is a huge risk.

The Anticancer Fund decided to bring information together in one place so that researchers could see at a glance what trials are ongoing or in preparation. Ideally this should result in more collaborations around the world.

The COVID-19 database is updated regularly, at least twice a week. The list provided is based on the trials registered in ClinicalTrials.gov (USA), the European Clinical Trials Register and the International Clinical Trials Platform from the World Health Organisation (WHO).

The focus is on existing drugs

It should be noted that the majority of the ongoing trials include repurposed drugs, or existing medicines that are already on the market to treat other diseases. Drug repurposing or drug repositioning is a cost-efficient way to find new treatment options and researchers can move forward very quickly as the drugs are already tested on safety.

Repurposed drugs are also used to treat cancer. The Anticancer Fund supports several clinical trials investigating the value of existing medicines in the treatment of cancer. So far we have identified over 300 drugs with the potential to be used as new cancer treatments. Further research is necessary, but these drugs could potentially increase the survival of cancer patients. The 300 drugs are listed in the Repurposing Drugs in Oncology (ReDO) database. Discover the database here: http://www.redo-project.org/db/ or read more about repurposed drugs here: https://www.anticancerfund.org/en/drug-repurposing.

“We might be an organisation focused on cancer treatments and cancer patients, we are nevertheless deeply concerned by the impact of the coronavirus and we want to contribute to a solution. We feel it’s our social responsibility to apply our skills in clinical research with repurposed drugs to COVID-19 and therefore hand researchers, clinicians and regulators a filtered listing, easy to read through”, said Lydie Meheus, managing director of the Anticancer Fund.

Important note: the list includes trials of drugs that, based on their scientific properties, warrant further scientific investigation. This list is not intended to be used as a source for possible treatment options for patients.

COVID-19 trials worldwide with repurposed drugs as hydrochloroquine

Cancer patients can reach out to us

The Anticancer Fund is available during the corona crisis and remains fully committed to its mission of helping cancer patients. If you have specific questions about your disease or treatment options, feel free to contact us. Click below to find out what we can do for you.