Latest news on drug repurposing in oncology | Anticancerfund

Latest news on drug repurposing in oncology

Drug repurposing is a strategy for identifying new uses for approved drugs, outside the scope of the original indication. We have listed recent findings about the repurposing of drugs in oncology. Our intention is to bring these findings to the attention of the broader cancer research community. 

Newsletters

Being listed in a newsletter is no endorsement of the results and conclusions of the article. All articles need to be critically assessed and viewed in their broader research context. 

Please get in touch if you’re interested in discussing research based on the findings presented below (info@anticancerfund.org).

#13

13-01-2022
Top story published in Cancer Cell: The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1

#12

26-11-2021
Top story published in Science Advances: The metabolic adaptation evoked by arginine enhances the effect of radiation in brain metastases

Drug repurposing in oncology newsletter #12

#11

22/10/2021
Top story published in Clinical Cancer Research: Losartan blocks osteosarcoma-elicited monocyte recruitment, and combined with the kinase inhibitor toceranib, exerts significant clinical benefit in canine metastatic osteosarcoma

Drug repurposing in oncology newsletter #11

#10

30-09-2021
Top story published in Neuro-Oncology Advances: A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3

Drug repurposing in oncology newsletter #10

#9

09-08-2021
Top story published in Frontiers in Oncology: Repurposing Infectious Diseases Vaccines Against Cancer

Drug repurposing in oncology newsletter #9

#8

23-06-2021
Top story published in Blood Cancer: Lenalidomide and dexamethasone with or without clarithromycin in patients with multiple myeloma ineligible for autologous transplant: a randomized trial.

Drug repurposing in oncology newsletter #8

#7

11-05-2021
Top story published in Jama: Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer

Drug repurposing in oncology newsletter #7

#6

12-04-2021
Top story published in British Journal of Haematology: Indomethacin is an effective treatment in adults and children with bone Langerhans cell histiocytosis (LCH).

Drug repurposing in oncology newsletter #6

#5

08-03-2021
Top story published in Clinical Cancer Research: Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non-Small Cell Lung Cancer.

Drug repurposing in oncology newsletter #5

#4

05-02-2021
Top story published in Cancer Cell: Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.

Drug repurposing in oncology newsletter #4

#3

15-01-2021
Top story published in Pediatric Blood & Cancer: Metro-SMHOP 01: Metronomics combination with cyclophosphamide-etoposide and valproic acid for refractory and relapsing pediatric malignancies.

Drug repurposing in oncology newsletter #3

#2

20-11-2020
Top story published in Clinical Cancer Research, the official journal of the American Association for Cancer Research: Phase I clinical trial of combination propranolol and pembrolizumab in locally advanced and metastatic melanoma: Safety, Tolerability, and Preliminary Evidence of Antitumor Activity

Drug repurposing in oncology newsletter #2

#1

19-10-2020
Top story published in the British Journal of Surgery: Influence of Klebsiella pneumoniae and quinolone treatment on prognosis in patients with pancreatic cancer.

Drug repurposing in oncology newsletter #1