Science resources
A list of scientific publications produced by researchers at the Anticancer Fund, or acknowledging our support.
Summary results as of last build on: 02/10/24 | Number | Percentage |
Total number of publications | 112 | |
Authored by ACF | 95 | 84.82% |
Acknowledges ACF support | 17 | 15.18% |
Full text available (open access) | 92 | 82.14% |
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Database build date: 02/10/24
Number of publications in database: 112 (Filter not active)
Authors | ACF Contribution | Title | Type | Journal/Conference | Pub Date | External Link | ACF Link | Full Text | Key Words |
---|---|---|---|---|---|---|---|---|---|
Julie De Smedt, Sofie Van Kelst, Laudine Janssen, Vivien Marasigan, Veerle Boecxstaens, Kris Bogaerts, Ann Belmans, Dirk Vanderschueren, Katleen Vandenberghe, Oliver Bechter, Claudia Aura, Diether Lambrechts, Tinne Strobbe, Gabriella Emri, Arjen Nikkels, Marjan Garmyn | Acknowledged | High-dose vitamin D supplementation does not improve outcome in a cutaneous melanoma population: results of a randomized double-blind placebo-controlled study (ViDMe trial) | Journal Article | British Journal of Dermatology | 2024-06-24 | Link | Link | N | Vitamin D3, melanoma, clinical trial |
G. Kuijten, J. Hermans, L. Vandeborne, K. Rombauts, G. Buyens, M. Bollue, P. Deroost, R. Janssens, I. Huys | Author | Impact of the free information service My Cancer Navigator according to patients and their relatives: An online survey | Journal Article | Annals of Oncology | 2024-09-16 | Link | Link | Y | Online survey, patient experience, My Cancer Navigator |
Darrell Green, Roelof van Ewijk, Elisa Tirtei, Dimosthenis Andreou, Fredrik Baecklund, Daniel Baumhoer, Stefan S Bielack, Rajesh Botchu, Kjetil Boye, Bernadette Brennan, Michael Capra, Lucia Cottone, Uta Dirksen, Franca Fagioli, Natalia Fernandez, Adrienne M Flanagan, Marco Gambarotti, Nathalie Gaspar, Hans Gelderblom, Craig Gerrand, Anne Gomez-Mascard, Jendrik Hardes, Stefanie Hecker-Nolting, Edita Kabickova, Leo Kager, Jukka Kanerva, Lennart A Kester, Marieke L Kuijjer, Valérie Laurence, Cyril Lervat, Antonin Marchais, Perrine Marec-Berard, Cristina Mendes, Johannes H M Merks, Benjamin Ory, Emanuela Palmerini, Pan Pantziarka, Evgenia Papakonstantinou, Sophie Piperno-Neumann, Anna Raciborska, Elizabeth A Roundhill, Vilma Rutkauskaite, Akmal Safwat, Katia Scotlandi, Eric L Staals, Sandra J Strauss, Didier Surdez, Gwen M L Sys, Marie-Dominique Tabone, Maud Toulmonde, Claudia Valverde, Michiel A J van de Sande, Klaus Woertler, Quentin Campbell-Hewson, Martin G McCabe, Michaela Nathrath | Author | Biological sample collection to advance research and treatment: a Fight Osteosarcoma Through European Research (FOSTER) and Euro Ewing Consortium (EEC) statement | Journal Article | Clinical Cancer Research | 2024-06-13 | Link | No link | Y | Sample collection, bone sarcomas, consensus statement, patient advocacy |
Silvia Stacchiotti, Gauthier Bouche, Ralf Herold, Pan Pantziarka, Kathrin Schuster, Roger Wilson, Francesco Pignatti, Bernd Kasper | Author | How to develop new systemic treatments in ultra-rare cancers with high unmet needs? The case of alveolar soft-part sarcoma | Journal Article | European Journal of Cancer | 2024-03-11 | Link | No link | N | Rare cancers, clinical trials, policy, methodology |
Denise Robinson, Hugh Leonard, Giacomo Giulio Baldi, William D Tap, Robin L Jones, Silvia Stacchiotti, Pan Pantziarka | Author | The patient perspective on sirolimus for epithelioid hemangioendothelioma (EHE): results of a community survey highlighting the importance of equitable access to treatments | Journal Article | Frontiers in Oncology | 2024-02-26 | Link | No link | Y | Sirolimus, EHE, drug repurposing, patient advocacy |
Miriam Dixon-Zegeye, Rachel Shaw, Linda Collins, Kendra Perez-Smith, Alexander Ooms, Maggie Qiao, Pan Pantziarka, Louise Izatt, Marc Tischkowitz, Rachel E Harrison, Angela George, Emma R Woodward, Simon Lord, Lara Hawkes, D Gareth Evans, James Franklin, Helen Hanson, Sarah P Blagden | Author | Cancer Precision-Prevention trial of Metformin in adults with Li Fraumeni syndrome (MILI) undergoing yearly MRI surveillance: a randomised controlled trial protocol | Journal Article | Trials | 2024-02-03 | Link | No link | Y | Li Fraumeni Syndrome, drug repurposing, clinical trial, cancer prevention |
Christelle Bouchart, Julie Navez, Ivan Borbath, Karen Geboes, Timon Vandamme, Jean Closset , Luigi Moretti, Pieter Demetter, Marianne Paesmans, Jean-Luc Van Laethem | Acknowledged | Preoperative treatment with mFOLFIRINOX or Gemcitabine/Nab-paclitaxel +/- isotoxic high-dose stereotactic body Radiation Therapy (iHD-SBRT) for borderline resectable pancreatic adenocarcinoma (the STEREOPAC trial): study protocol for a randomised comparative multicenter phase II trial | Journal Article | BMC Cancer | 2023-09-21 | Link | No link | Y | Pancreatic cancer, Radiotherapy, Clinical trial |
Ian F. Tannock, Gauthier Bouche, Daniel A. Goldstein, Yasushi Goto, Allen S. Lichter, Kumar Prabhash, Priya Ranganathan, Leonard B. Saltz, Gabe S. Sonke, Garth W. Strohbehn, Roger von Moos, Mark J. Ratain | Author | Patient-centred, self-funding dose optimisation trials as a route to reduce toxicity, lower cost and improve access to cancer therapy | Journal Article | Annals of Oncology | 2023-05-22 | Link | No link | N | Clinical trials, Policy, Methodology |
Pan Pantziarka, Ian Roberts, Patricia Vandamme, Lydie Meheus, Gauthier Bouche | Author | Drug evidence watch: a process to the benefit of public health | Journal Article | The Lancet | 2023-04-12 | Link | No link | Y | Drug development, drug repurposing, medical regulation, health policy |
Pierre Leblond, Emmanuelle Tresch-Bruneel, Alicia Probst, Nadège Néant, Caroline Solas, Arthur Sterin, Thomas Boulanger, Isabelle Aerts, Cécile Faure-Conter, Anne-Isabelle Bertozzi, Pascal Chastagner, Natacha Entz-Werlé, Emilie De Carli, Marie-Cécile Le Deley, Gauthier Bouche, Nicolas André | Author | Phase I study of a combination of fluvastatin and celecoxib in 2 children with relapsing/refractory low-grade or high-grade gli-3 oma (FLUVABREX) | Journal Article | Cancers | 2023-03-28 | Link | No link | N | Clinical trial, drug repurposing, pediatric cancer |
Nicolas André, Guy Buyens, Eric Bouffet, David Walker, Matthew D Dun | Author | Access to new drugs in paediatric oncology: can we learn from the ongoing ONC201 saga? | Journal Article | Lancet Oncology | 2023-02-14 | Link | No link | N | Drug development, pediatric oncology, ONC201, DIPG/DMG |
Elizabeth Ann Roundhill, Pan Pantziarka, Danielle E. Liddle, Lucy A. Shaw, Ghadeer Albadrani and Susan Ann Burchill | Author | Exploiting the Stemness and Chemoresistance Transcriptome of Ewing Sarcoma to Identify Candidate Therapeutic Targets and Drug‐Repurposing Candidates | Journal Article | Cancers | 2023-01-26 | Link | No link | Y | Ewing sarcoma, stemness, pluripotency, CD133, multidrug resistance, ABCG1, POU5F1/CT-4, drug repurposing |
Guy Buyens, Michael van Balken, Kathy Oliver, Richard Price, Lawler M, Nicolò Matteo Luca Battisti, Hein Van Poppel, Enea Venegonie | Author | Cancer literacy - Informing patients and implementing shared decision making | Journal Article | Journal of Cancer Policy | 2022-12-01 | Link | No link | N | Health literacy, shared decision making, patient support, patient education |
Gauthier Bouche, Ruth Langley, Hannah Rush, Mahesh Parmar, Duncan C. Gilbert | Author | Testing alternative schedules of adjuvant immune checkpoint blockers – The need for well-designed clinical trials | Journal Article | European Journal of Cancer | 2022-11-22 | Link | No link | N | Clinical trial design, methodology |
Elisabeth De Waele, Joy Demol, Koen Huysentruyt, Geir Bjørklund, Ronald Buyl, Alessandro Laviano and Joeri J. Pen | Acknowledged | Nutrition Therapy Promotes Overall Survival in Cachectic Cancer Patients through a New Proposed Chemical-Physical Pathway: The TiCaCONCO Trial (A Randomized Controlled Single-Blinded Trial) | Journal Article | Appetite | 2022-11-01 | Link | No link | N | Cancer cachexia, nutrition, randomised trial, TiCaCONCO trial |
Hendrik Van Poppel, MD, PhD; Nicolo Matteo Luca Battisti, MD; Mark Lawler, PhD; Teodora Kolarova, MA; Jacqueline Daly, BSc; Katie Rizvi, BSc; Robert Greene, BSc; Guy Buyens, MD; Kathy Oliver, BSc; Richard Price, BA; Nela Osmanovic, MSc; Enea Venegoni, BSc | Author | European Cancer Organisation’s Inequalities Network: Putting Cancer Inequalities on the European Policy Map | Journal Article | JCO Global Oncology | 2022-10-17 | Link | No link | Y | Health inequalities, cancer, health policy, European Cancer Organisation |
Rica Capistrano I, Sonz Paul, Ingrid Boere, Pan Pantziarka, Supriya Chopra, Remi A Nout and Gauthier Bouche | Author | Drug repurposing as a potential source of innovative therapies in cervical cancer | Journal Article | Intl Journal of Gynecological Cancer | 2022-09-22 | Link | Link | Y | Cervical cancer, drug repurposing |
Charlotte Ouimet,Gauthier Bouche, Jonathan Kimmelman | Author | Diminishing clinical impact for post-approval cancer clinical trials: A retrospective cohort study | Journal Article | PLoS ONE | 2022-09-12 | Link | No link | Y | Drug approvals, drug repurposing, cancer policy, regulatory science |
Emiel A. De Jaeghere, Sandra Tuyaerts, An M. T. Van Nufel, Ann Belmans, Kris Bogaerts, Regina Baiden‑Amissah, Lien Lippens, Peter Vuylsteke, Stéphanie Henry, Xuan Bich Trinh, Peter A. van Dam, Sandrine Aspeslagh, Alex De Caluwé, Eline Naert, Diether Lambrechts, An Hendrix, Olivier De Wever, Koen K. Van de Vijver, Frédéric Amant, Katrien Vandecasteele, Hannelore G. Denys | Author | Pembrolizumab, radiotherapy, and an immunomodulatory five‑drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma: Results of the phase II PRIMMO study | Journal Article | Cancer Immunology, Immunotherapy | 2022-08-12 | Link | Link | Y | Computational model, mathematical oncology, evolutionary algorithm, machine learning |
Pan Pantziarka, Lina Ghibelli, Albrecht Reichle | Author | The Effect of Over-Feeding in a Computational Model of Tumour Growth | Journal Article | Cancer, Complexity, Computation (book) | 2022-08-12 | Link | No link | N | Computational model, mathematical oncology, evolutionary algorithm, machine learning |
Maud Toulmonde, Perrine Marec-Berard, Cyril Lervat, Coralie Cantarel, Emilie Toulza, Sabrina Sellan-Albert, Sophie Cousin, Kevin Bourcier, Mariella Spalato-Ceruso, Raul Perret, Simone Mathoulin-Pelissier, Jean-Yves Blay, Nicolas Penel, Carine Bellera and Antoine Italiano | Acknowledged | METZOLIMOS Metronomic Cyclophosphamide (CP) and Methotrexate (MTX) combined with Zoledronic Acid (ZA) and Sirolimus (SIR) in patients with advanced Solid Tumor with bone metastasis and advanced pretreated Osteosarcoma (OSS) A Phase Ib Study | Poster | ASCO 2022 | 2022-06-09 | Link | Link | Y | Osteosarcoma, drug repurposing, clinical trial results, ASCO |
Pamela M. J. McLaughlin, Maximilian Klar, Tibor A. Zwimpfer, Gilles Dutilh, Marcus Vetter, Christian Marth, Andreas du Bois, Carmen Schade‑Brittinger, Alexander Reuss, Claudine Bommer, Christian Kurzeder and Viola Heinzelmann‑Schwarz | Acknowledged | Maintenance Therapy with Aromatase Inhibitor in epithelial Ovarian Cancer (MATAO): study protocol of a randomized double‑blinded placebo‑controlled multi‑center phase III Trial | Journal Article | BMC Cancer | 2022-05-06 | Link | No link | Y | Ovarian cancer, clinical trial protocol, letrozole |
Julie De Smedt, Sofie Van Kelst, Laudine Janssen, Vivien Marasigan, Veerle Boecxstaens, Marguerite Stas, Dirk Vanderschueren, Ipek Guler, Kris Bogaerts, Katleen Vandenberghe, Olivier Bechter, Jaak Billen, Arjen Nikkels, Tine Strobbe, Gabriella Emri, Diether Lambrechts, Marjan Garmyn | Acknowledged | Determinants of 25-hydroxyvitamin D Status in a Cutaneous Melanoma Population | Journal Article | Advances in Dermatology and Venereology | 2022-03-21 | Link | Link | Y | melanoma; vitamin D; body mass index |
Gauthier Bouche, Lydie Meheus | Author | Ensuring completeness and timeliness of cancer treatment guidelines | Journal Article | Nature Reviews Clinical Oncology | 2022-05-20 | Link | Link | N | Cancer treatment, treatment guidelines, patient access, drug repurposing |
Pan Pantziarka, Sarah Blagden | Author | Inhibiting the Priming for Cancer in Li-Fraumeni Syndrome | Journal Article | Cancers | 2022-03-23 | Link | No link | Y | Li Fraumeni Syndrome, precancerous niche, drug repurposing |
Charlotte Asker-Hagelberg, Tomas Boran, Christelle Bouygues, Sini Marika Eskola, Laszlo Helmle, César Hernández, François Houÿez, Helen Lee, Dimitra D. Lingri, Laurent Louette, Lydie Meheus, Wim Penninckx and Beata Stepniewska | Author | Repurposing of Medicines in the EU: Launch of a Pilot Framework | Journal Article | Frontiers in Medicine | 2022-01-10 | Link | No link | Y | Drug repurposing, cancer policy, regulatory science |
Pan Pantziarka, Liese Vandeborne and Gauthier Bouche | Author | A Database of Drug Repurposing Clinical Trials in Oncology | Journal Article | Frontiers in Pharmacology | 2021-11-10 | Link | No link | Y | Drug repurposing, Clinical trials, database |
P Leblond, A Probst, N Entz-Werlé, AS Defachelles, I Aerts, E Bogart, AM Bimbai, MC Le Deley, N André | Acknowledged | METRO-PD1: A Phase I Feasibility Study Evaluating Anti-PD1 (NIVOLUMAB) In Combination With Metronomic Chemotherapy In Children And Teenagers With Refractory/Relapsing Solid Tumors Or Lymphoma | Poster | SIOP 2021 | 2021-10-21 | No link | Link | Y | Clinical trial, drug repurposing, checkpoint inhibitors, pediatric cancer |
Rica Capistrano, Sonz Paul, Ingrid A. Boere, Pan Pantziarka, Supriya Chopra, Remi A. Nout, Gauthier Bouche | Author | Drug repurposing as a source of innovative therapies in cervical cancer | Poster | ESGO 2021 | 2021-10-23 | No link | Link | Y | Cervical cancer, drug repurposing |
Sergio Crispino, Klara Rombauts, Pan Pantziarka, Gauthier Bouche | Author | Drug repurposing candidates in the treatment of brain metastases | Poster | Brain Metastases Research and Emerging Therapy Conference | 2021-09-29 | No link | Link | Y | Brain metastases, drug repurposing, new treatment options |
Bishal Gyawali, Richard Sullivan, Christopher M Booth | Acknowledged | Cancer groundshot: going global before going to the moon | Journal Article | Lancet Oncology | 2018-03-19 | Link | Link | Y | Cancer policy, global health, patient benefit |
Marc-Eric Halatsch, Richard E. Kast, Georg Karpel-Massler, Benjamin Mayer, Oliver Zolk, Bernd Schmitz, Angelika Scheuerle, Ludwig Maier, Lars Bullinger, Regine Mayer-Steinacker, Carl Schmidt, Katharina Zeiler, Ziad Elshaer, Patricia Panther, Birgit Schmelzle, Anke Hallmen, Annika Dwucet, Markus D. Siegelin, Mike-Andrew Westhoff, Kristine Beckers, Gauthier Bouche, and Tim Heiland | Author | A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3 | Journal Article | Neuro-Oncology Advances | 2021-08-07 | Link | Link | Y | Glioblastoma Multiforme, GBM, drug repurposing, CUSP9v3, clinical trial |
Sandrina Martens, Katarina Coolens, Mathias Van Bulck, Tatjana Arsenijevic, Joan Casamitjana, Angel Fernandez Ruiz, Abdessamad El Kaoutari, Jaime Martinez de Villareal, Hediel Madhloum, Farzad Esni, Yves Heremans, Gunter Leuckx, Harry Heimberg, Luc Bouwens, Patrick Jacquemin, Diedert Luc De Paep, Peter in't Veld, Nicky D'Haene, Christelle Bouchart, Nelson Dusetti, Jean-Luc Van Laethem, Wim Waelput, Pierre Lefesvre, Francisco X Real, Meritxell Rovira, Ilse Rooman | Author | Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease | Journal Article | Gut | 2021-07-30 | Link | Link | Y | Pancreatic cancer, basic science, animal models, basal-like molecular subtype |
Nathalie C Støer, Gauthier Bouche, Pan Pantziarka, Erica K Sloan, Bettina K Andreassen, Edoardo Botteri | Author | Use of non-cancer drugs and survival among patients with pancreatic adenocarcinoma: a nationwide registry-based study in Norway | Journal Article | Acta Oncologica | 2021-08-02 | Link | Link | N | Retrospective study, drug repurposing, statins, pancreatic cancer |
Gauthier Bouche, Eric Bouffet, Liese Vandeborne, Rica Capistrano, Nicolas André | Author | Diffuse intrinsic pontine glioma: a clinic in Mexico, social media, and unpublishable data | Journal Article | Lancet Oncology | 2021-05-22 | Link | No link | Y | Pediatric cancer, ethics, perspective, diffuse intrinsic pontine glioma, Mexican clinics |
Liese Vandeborne, Pan Pantziarka, An M. T. Van Nuffel and Gauthier Bouche | Author | Repurposing Infectious Diseases Vaccines Against Cancer | Journal Article | Frontiers in Oncology | 2021-05-13 | Link | Link | Y | Infectious diseases vaccines, drug repurposing, immunotherapy |
Ciska Verbaanderd, Ilse Rooman, Isabelle Huys | Author | Exploring new uses for existing drugs: Innovative mechanisms to fund independent clinical research | Journal Article | Trials | 2021-05-04 | Link | Link | Y | Drug repurposing, clinical trials, health economics, trialfunding |
Elena Vagia, Massimo Cristofanilli | Acknowledged | New Treatment Strategies for the Inflammatory Breast Cancer | Journal Article | Current Treatment Options in Oncology | 2021-04-24 | Link | No link | Y | Inflammatory breast cancer, clinical trial design, review |
John A Hickman, Ian F Tannock, Lydie Meheus, Lisa Hutchinson | Author | The European Union and personalised cancer medicine | Journal Article | European Journal of Cancer | 2021-04-20 | Link | No link | N | Personalised medicine, health policy, clinical trial design |
Daniel Heudoble, Christian Schulz, Jürgen R. Fischer, Peter Staib, Thomas Wehler, Thomas Südhoff, Thomas Schichtl, Jochen Wilke, Joachim Hahn, Florian Lüke, Martin Vogelhuber, Sebastian Klobuch, Tobias Pukrop, Wolfgang Herr, Swantje Held, Kristine Beckers, Gauthier Bouche, Albrecht Reichle | Author | A Randomized Phase II Trial Comparing the Efficacy and Safety of Pioglitazone, Clarithromycin and Metronomic Low-Dose Chemotherapy with Single-Agent Nivolumab Therapy in Patients with Advanced Non-small Cell Lung Cancer Treated in Second or Further Line (ModuLung) | Journal Article | Frontiers in Pharmacology | 2021-03-16 | Link | Link | Y | Anakoinosis, clinical trial, non-small cell lung cancer |
Pan Pantziarka, Rica Capistrano I, Arno De Potter, Liese Vandeborne and Gauthier Bouche | Author | An Open Access Database of Licensed Cancer Drugs | Journal Article | Frontiers in Pharmacology | 2021-03-11 | Link | Link | Y | Repurposing, cancer drugs, pharmacology |
Rachel Abudu, BS, MPH; Gauthier Bouche, MPH, MD; Karima Bourougaa, PhD; Lynne Davies, PhD; Kalina Duncan, BS, MPH; Carla Estaquio, PhD; Anna Diaz Font, PhD; Marc S. Hurlbert, PhD; Paul Jackson, PhD; Linda Kroeskop-Bossenbroek, PhD; Ian Lewis, PhD; Giota Mitrou, PhD; Abdul Mutabbir, BSc; Christopher A. Pettigrew, PhD; Lynn Turner, PhD; Annemarie Weerman, PhD; and Kari Wojtanik, PhD | Author | Trends in International Cancer Research Investment 2006-2018 | Journal Article | JCO Global Oncology | 2021-03-10 | Link | Link | Y | Clinical trial funding, research trends, international comparisons |
Christoffer Gebhardt, Sonja C S Simon, Rebekka Weber, Mirko Gries, Dong Hun Mun, Raphael Reinhard, Tim Holland-Letz, Viktor Umansky, Jochen Utikal | Acknowledged | Potential therapeutic effect of low-dose paclitaxel in melanoma patients resistant to immune checkpoint blockade: A pilot study | Journal Article | Cellular Immunology | 2020-12-28 | Link | Link | N | Metronomic chemotherapy, melanoma, clinical trial, immuno-modulation |
Gauthier Bouche, Craig Gedye, Lydie Meheus, Pan Pantziarka | Author | Drug repurposing in oncology | Journal Article | Lancet Oncology | 2020-12-01 | Link | No link | Y | Correspondence, drug repurposing |
Sergio Crispino, Pan Pantziarka, Lydie Meheus, Gauthier Bouche | Author | Finding existing drugs potentially active against BRCA mutated breast cancers: a literature based approach | Poster | EBCC-12 | 2020-10-01 | Link | Link | Y | Breast cancer, drug repurposing, literature search |
Felix J Hüttner, Ilse Rooman, Gauthier Bouche, Phillip Knebel, Johannes Hüsing, André L Mihaljevic, Thilo Hackert, Oliver Strobel, Markus W Büchler, Markus K Diener | Author | Pancreatic resection with perioperative drug repurposing of propranolol and etodolac: trial protocol of the phase-II randomised placebo controlled PROSPER trial | Journal Article | BMJ Open | 2020-09-30 | Link | Link | Y | pancreatic cancer, trial protocol, drug repurposing, propranolol, etodolac, PROSPER |
Benson Chellakkan Selvanesan, Kiran Meena, Amanda Beck, Lydie Meheus, Olaya Lara, Ilse Rooman, Claudia Gravekamp | Author | Nicotinamide combined with gemcitabine is an immunomodulatory therapy that restrains pancreatic cancer in mice | Journal Article | Journal for Immunotherapy for Cancer | 2020-09-29 | Link | Link | Y | Pancreatic cancer, nicotinamide, immunomodulatory therapy, drug repurposing, preclinical |
Ciska Verbaanderd | Author | ReDIReCT - Repurposing of Drugs: Innovative Revision of Cancer Treatment | Thesis | 2020-09-24 | No link | Link | Y | drug repositioning, drug repurposing, off-label use, oncology, policy recommendations, regulatory framework, investigator-initiated studies, research funding, off-patent medicines | |
Heinhuis KM, IJzerman NS, Koenen AM, et al. | Acknowledged | PropAngio study protocol: a neoadjuvant trial on the efficacy of propranolol monotherapy in cutaneous angiosarcoma—a proof of principle study | Journal Article | BMJ Open | 2020-09-18 | Link | Link | Y | Angiosarcoma, drug repurposing, study protocol, trial protocol, PropAngio |
Rita Ahmed, Isaac Crespo, Sandra Tuyaerts, Amel Bekkar, Michele Graciotti, Ioannis Xenarios, Lana E. Kandalaft | Acknowledged | Predicting combinations of immunomodulators to enhance dendritic cell-based vaccination based on a hybrid experimental and computational platform. | Journal Article | Computational and Structural Biotechnology Journal | 2020-08-08 | Link | Link | Y | Dendritic cell vaccines, immunomodulatory therapy |
Andrea Spini, Sandra Donnini, Pan Pantziarka, Sergio Crispino, Marina Ziche | Author | Repurposing of drugs for triple negative breast cancer: an overview | Journal Article | Ecancermedicalscience | 2020-07-13 | Link | Link | Y | Triple negative breast cancer, drug repurposing |
Els Verdegaal, Monique K van der Kooij, Marten Visser, Caroline van der Minne, Linda de Bruin, Pauline Meij, Anton Terwisscha van Scheltinga, Marij J Welters, Saskia Santegoets, Noel de Miranda, Inge Roozen, Gerrit Jan Liefers, Ellen Kapiteijn and Sjoerd H van der Burg | Acknowledged | Low-dose interferon-alpha preconditioning and adoptive cell therapy in patients with metastatic melanoma refractory to standard (immune) therapies: a phase I/II study | Journal Article | Journal for ImmunoTherapy of Cancer | 2020-04-01 | Link | Link | Y | metastatic melanoma, interferon-alpha, adoptive cell therapy, trial results |
Christina Friese, Katja Harbst, Troels Holz Borch, Marie Christine Wulff Westergaard, Magnus Pedersen, Anders Kverneland, Göran Jönsson, Marco Donia, Inge Marie Svane, Özcan Met | Acknowledged | CTLA-4 blockade boosts the expansion of tumor-reactive CD8+ tumor-infiltrating lymphocytes in ovarian cancer | Journal Article | Scientific Reports | 2020-03-03 | Link | Link | Y | recurrent ovarian cancer, Immune therapy, preclinical |
Bishal Gyawali, Gauthier Bouche, Nigel Crisp and Nicolas André | Author | Challenges and opportunities for cancer clinical trials in low- and middle-income countries | Journal Article | Nature Cancer | 2020-02-17 | Link | Link | Y | cancer, trial development, low- and middle-income countries |
Ciska Verbaanderd, Ilse Rooman, Lydie Meheus, Isabelle Huys | Author | On-Label or Off-Label? Overcoming Regulatory and Financial Barriers to Bring Repurposed Medicines to Cancer Patients | Journal Article | Frontiers in Pharmacology | 2020-01-31 | Link | Link | Y | Drug repurposing, regulatory and financial barriers |
Pan Pantziarka, Ciska Verbaanderd, Isabelle Huys, Gauthier Bouche, Lydie Meheus | Author | Repurposing drugs in oncology: From candidate selection to clinical adoption | Journal Article | Seminars in Cancer Biology | 2020-01-23 | Link | No link | Y | Review, drug repurposing |
Bart J.T. Reymen, Marike W. van Gisbergen, Aniek J.G. Even, Catharina M.L. Zegers, Marco Das, Erik Vegt, Joachim E. Wildberger, Felix M. Mottaghy, Ala Yaromina, Ludwig J. Dubois, Wouter van Elmpt, Dirk De Ruysscher, Philippe Lambin | Acknowledged | Nitroglycerin as a radiosensitizer in non-small cell lung cancer: Results of a prospective imaging-based phase II trial | Journal Article | Clinical and Translational Radiation Oncology | 2019-12-13 | Link | Link | Y | non-small cell lung cancer, trial results, nitroglycerin, drug repurposing |
Pan Pantziarka, Ciska Verbaanderd, Lydie Meheus | Author | Biased by design? Clinical trials and patient benefit in oncology | Journal Article | Future Medicine | 2019-12-11 | Link | Link | Y | clinical trials, bias |
Daniel Heudobler, Sebastian Klobuch, Florian Lüke, Joachim Hahn, Matthias Grube, Stephan Kremers, Thomas Südhoff, Jörg Westermann, Marie Luise Hütter-Krönke, Peter Paschka, Gauthier Bouche, Hartmut Döhner, Wolfgang Herr, Simone Thomas, Albrecht Reichle | Author | Low-dose azacytidine, pioglitazone and retinoic acid in ≥ 60 years patients with acute myeloid leukaemia refractory to chemotherapy (AML-ViVA) | Poster | ASH 2019 | 2019-12-09 | No link | Link | Y | acute myeloid leukemia, drug repurposing, azacitidine, retinoic acid, pioglitazone, AML-ViVA, trial results |
Maria E Goossens, Marc Van den Bulcke, Thierry Gevaert, Lydie Meheus, Dirk Verellen, Jean-Marc Cosset, and Guy Storme | Author | Is there any benefit to particles over photon radiotherapy? | Journal Article | Ecancermedicalscience | 2019-12-09 | Link | No link | Y | Review, radiotherapy |
Patrice Forget, Gauthier Bouche, Francois P. Duhoux, Pierre G. Coulie,Jan Decloedt, Alain Dekleermaker, Jean-Edouard Guillaume, Marc Ledent, Jean- Pascal Machiels, Véronique Mustin, Walter Swinnen, Aline van Maanen, Lionel Vander Essen, Jean-Christophe Verougstraete, Marc De Kock, Martine Berliere | Author | Intraoperative ketorolac in high-risk breast cancer patients. A prospective, randomized, placebo-controlled clinical trial | Journal Article | PLoS ONE | 2019-12-04 | Link | Link | Y | trial results, breast cancer, ketorolac |
Pan Pantziarka, Lydie Meheus | Author | Journal retractions in oncology: a bibliometric study | Journal Article | Future Medicine | 2019-11-29 | Link | Link | Y | retracted articles, misinformation |
N. André, A. Sterin, C. Solas, M.C. Le Deley, E. Tresch Bruneel, A. Probst, I. Aerts, C. Faure-Conter, A.I. Bertozzi, P. Chastagner, N. EntzWerlé, E. De Carli, G. Bouche, P. Leblond | Author | Phase I Study of Fluvastatin/Celecoxib Combination in Children with Relapsing or Refractory Low or High Grade Glioma - First Results | Poster | SIOP 2019 | 2019-11-26 | No link | Link | Y | trial results, paediatric glioma, Fluvabrex, drug repurposing |
Daniel Heudobler, Christian Schulz, Jürgen R. Fischer, Peter Staib, Thomas Wehler, Thomas Südhoff, Thomas Schichtl, Jochen Wilke, Joachim Hahn, Florian Lüke, Martin Vogelhuber, Sebastian Klobuch, Tobias Pukrop, Wolfgang Herr, Swantje Held, Kristine Beckers, Gauthier Bouche, Albrecht Reichle | Author | Pioglitazone and clarithromycin combined with metronomic chemotherapy vs. nivolumab in patients with advanced non-small-cell lung cancer: Outcomes from a randomized phase II trial (ModuLung) | Poster | ESMO 2019 | 2019-09-28 | No link | Link | Y | non-small cell lung cancer, trial results, drug repurposing, ModuLung |
Bishal Gyawali, Gauthier Bouche, Pan Pantziarka, Aaron S. Kesselheim, Ameet Sarpatwari | Author | Lung Cancer Survival Gains: Contributions of Academia and Industry | Journal Article | The Journal of Law, Medicine & Ethics | 2019-09-27 | Link | Link | Y | lung cancer |
An M. T. Van Nuffel, Caroline Boudousquié, Sandra Tuyaerts | Author | Approaches to Advance Cancer Vaccines to Clinical Utility | Journal Article | Frontiers in Immunology | 2019-08-27 | Link | Link | Y | cancer vaccines, editorial |
Pan Pantziarka, Nicolas André | Author | Drug Repurposing | Journal Article | Frontiers in Medicine | 2019-07-03 | Link | Link | Y | drug repurposing, editorial |
Sandra Tuyaerts, An M T Van Nuffel, Eline Naert, Peter A Van Dam, Peter Vuylsteke, Alex De Caluwé, Sandrine Aspeslagh, Piet Dirix, Lien Lippens, Emiel De Jaeghere, Frédéric Amant, Katrien Vandecasteele, Hannelore Denys | Author | PRIMMO Study Protocol: A Phase II Study Combining PD-1 Blockade, Radiation and Immunomodulation to Tackle Cervical and Uterine Cancer BMC Cancer | Journal Article | BMC Cancer | 2019-05-28 | Link | Link | Y | Immune therapy, drug repurposing, PRIMMO, cervical cancer, uterine cancer, trial protocol |
Pan Pantziarka, Gauthier Bouche | Author | Perioperative therapies - Using repurposed drugs to improve cancer surgery outcomes | Journal Article | The Cancer Journal | 2019-04-10 | Link | Link | Y | Drug repurposing, perioperative therapy |
A. Spini, G. Roberto, R. Gini, C. Bartolini, L. Bazzani, S. Donnini, S. Crispino, M. Ziche | Author | Evidence of β-blockers drug repurposing for the treatment of triple negative breast cancer: A systematic review | Journal Article | Neoplasma | 2019-03-28 | Link | Link | Y | Triple negative breast cancer, drug repurposing, beta-blockers, review |
Marie Christine Wulff Westergaard, Rikke Andersen, Chloé Chong, Julie Westerlin Kjeldsen, Magnus Pedersen, Christina Friese, Thomas Hasselager, Henrik Lajer, George Coukos, Michal Bassani-Sternberg, Marco Donia, Inge Marie Svane | Acknowledged | Tumour-reactive T Cell Subsets in the Microenvironment of Ovarian Cancer | Journal Article | British Journal of Cancer | 2019-02-19 | Link | Link | Y | ovarian cancer, immune therapy |
Tuyaerts, S., Rombauts, K., Everaert, T., Van Nuffel, AMT. and Amant, F. | Author | A Phase 2 Study to Assess the Immunomodulatory Capacity of a Lecithin-based Delivery System of Curcumin in Endometrial Cancer | Journal Article | Frontiers in Nutrition | 2019-01-11 | Link | Link | Y | Endometrial cancer, trial results, curcumin |
Pantziarka, P., Verbaanderd, C., Sukhatme, V., Capistrano, R., Crispino, S. Gyawali, B., Rooman, I., Van Nuffel, A. MT., Meheus, L., Sukhatme, V. P., & Bouche, G. | Author | ReDO_DB: the repurposing drugs in oncology database | Journal Article | Ecancermedicalscience | 2018-12-06 | Link | Link | Y | database, drug repurposing |
Forget Patrice, Bouche Gauthier, Duhoux Francois P., Coulie Pierre G., Decloedt Jan, Dekleermaker Alain, Guillaume Jean-Edouard, Ledent Marc, Machiels Jean-Pascal, Mustin Véronique, Swinnen Walter, Van Maanen Aline, Vander Essen Lionel, Verougstraete Jean-Christophe, De Kock Marc, Berliere Martine | Author | Intraoperative ketorolac in high-risk breast cancer patients with and without inflammation | Poster | SABCS 2018 | 2018-12-05 | No link | Link | Y | breast cancer, ketorolac, trial results, drug repurposing |
Pan Pantziarka, Gauthier Bouche | Author | Drug Repurposing as a Source of Innovative Therapies in Chondrosarcoma | Poster | CTOS 2018 | 2018-11-15 | No link | Link | Y | chondrosarcoma, drug repurposing |
Gauthier Bouche, Pan Pantziarka | Author | Multi-arm Trial in Localized Osteosarcoma: Moving from a Dream to Reality | Poster | CTOS 2018 | 2018-11-15 | No link | Link | Y | osteosarcoma, MAMS, PRESTO, trial design |
Magnus Pedersen, Marie Christine Wulff Westergaard, Katy Milne, Morten Nielsen, Troels Holz Borch, Lars Grønlund Poulsen, Helle Westergren Hendel, Mia Kennedy, Gillian Briggs, Stacey Ledoux, Trine Jakobi Nøttrup, Pernille Andersen, Thomas Hasselager, Özcan Met, Brad H Nelson, Marco Donia, Inge Marie Svane. | Acknowledged | Adoptive Cell Therapy With Tumor-Infiltrating Lymphocytes in Patients With Metastatic Ovarian Cancer: A Pilot Study | Journal Article | OncoImmunology | 2018-09-26 | Link | Link | Y | ovarian cancer, immune therapy, adoptive cell therapy, trial results |
An M.T. Van Nuffel, Sandra Tuyaerts, Peter Van Dam, Peter Vuylsteke, Alex De Caluwé, Piet Dirix, Katrien Vandecasteele, Hannelore Denys | Author | Adding 5 immunomodulators to radio- and immunotherapy without further increasing financial toxicity | Poster | ImmunoRad 2018 | 2018-09-20 | No link | Link | Y | PRIMMO, interim trial results, drug repurposing, cervical cancer, endometrial cancer, immune therapy |
Pantziarka, P. & Meheus, L. | Author | Omics-driven drug repurposing in rare cancers | Journal Article | Expert Opinion on Orphan Drugs | 2018-07-24 | Link | Link | N | rare cancers, drug repurposing |
Pantziarka, P., Pirmohamed, M., & Mirza, N. | Author | New uses for old drugs | Journal Article | BMJ | 2018-06-26 | Link | Link | N | drug repurposing |
Pantziarka, P., Bryan, B. A., Crispino, S., & Dickerson, E. B. | Author | Propranolol and breast cancer—a work in progress | Journal Article | Ecancermedicalscience | 2018-06-18 | Link | Link | Y | breast cancer, drug repurposing, propranolol |
Pan Pantziarka, Rica Capistrano I., Gauthier Bouche, Ilse Rooman | Author | Drug Repurposing as a Source of Innovative Therapies in Pancreatic Cancer | Poster | EPC 2018 | 2018-06-14 | No link | Link | Y | Pancreatic cancer, drug repurposing |
Pantziarka, P., Bouche, G., & André, N. | Author | “Hard” Drug Repurposing for Precision Oncology: The Missing Link? | Journal Article | Frontiers in Pharmacology | 2018-06-14 | Link | Link | Y | Drug repurposing, opinion article |
Gauthier Bouche, Pan Pantziarka | Author | Drug Repurposing as a Source of Innovative Therapies in Osteosarcoma | Poster | ASCO18 | 2018-06-02 | No link | Link | Y | osteosarcoma, drug repurposing |
Pantziarka, P., Sukhatme, V., Crispino, S., Bouche, G., Meheus, L., & Sukhatme, V. P. | Author | ReDO: selective PDE5 inhibitors as anti-cancer agents | Journal Article | Ecancermedicalscience | 2018-04-11 | Link | Link | Y | drug repurposing, PDE5 inhibitors, ReDO project |
Sergio Crispino, Lydie Meheus, Pan Pantziarka, Bishal Gyawali, Gauthier Bouche | Author | Repurposing non-cancer drugs for breast cancer? An emerging opportunity. | Poster | EBCC-11 | 2018-03-21 | No link | Link | Y | Breast cancer, drug repurposing |
Bishal Gyawali, Pan Pantziarka, Sergio Crispino, Gauthier Bouche | Author | Does the oncology community have a rejection bias when it comes to repurposed drugs? | Journal Article | Ecancermedicalscience | 2018-01-16 | Link | No link | Y | Drug repurposing, commentary |
Verbaanderd, C., Maes, H., Schaaf, M. B., Sukhatme, V. P., Pantziarka, P., Sukhatme, V., Agostinis, P., & Bouche, G. | Author | ReDO: (hydroxy)chloroquine as anti-cancer agents | Journal Article | Ecancermedicalscience | 2017-11-23 | Link | Link | Y | drug repurposing, hydroxychloroquine, chloroquine, ReDO project |
Pantziarka, P., Bouche, G., Sullivan, R., Ilbawi, A.M., Dare, A.J., & Meheus, L. | Author | Perioperative therapies – Enhancing the impact of cancer surgery with repurposed drugs | Journal Article | European Journal of Surgical Oncology | 2017-11-01 | Link | Link | Y | Perioperative therapy, drug repurposing |
Bouche, G., Crisp, N., Gyawali, B., & André, N. | Author | Tap latent source of frugal cancer ideas. | Journal Article | Nature | 2017-10-12 | Link | Link | Y | drug repurposing, letter |
Verbaanderd, C., Meheus, L., Huys, I., & Pantziarka, P. | Author | Repurposing Drugs in Oncology: Next Steps | Journal Article | Trends in Cancer | 2017-07-12 | Link | Link | Y | drug repurposing, financial and regulatory hurdles |
Pantziarka, P. | Author | Scientific advice — is drug repurposing missing a trick? | Journal Article | Nature Reviews Clinical Oncology | 2017-05-23 | Link | Link | N | drug repurposing, scientific advice |
Pantziarka, P. | Author | On paranoid parents | Journal Article | Pediatric Blood & Cancer | 2017-01-17 | Link | Link | N | ovarian cancer, sarcoma, parental paranoia |
Pan Pantziarka, Lisa Hutchinson, Nicolas André, Sébastien Benzekry, Francesco Bertolini, Atanu Bhattacharjee, Shubhada Chiplunkar, Dan G. Duda, Vikram Gota, Sudeep Gupta, Amit Joshi, Sadhana Kannan, Robert Kerbel, Mark Kieran, Antonella Palazzo, Aparna Parikh, Eddy Pasquier, Vijay Patil, Kumar Prabhash, Yuval Shaked, Giselle Saulnier Sholler, Jaroslav Sterba, David J. Waxman, and Shripad Banavali | Author | Next generation metronomic chemotherapy-report from the Fifth Biennial International Metronomic and Anti-angiogenic Therapy Meeting, 6-8 May 2016, Mumbai | Journal Article | Ecancermedicalscience | 2016-11-02 | Link | No link | Y | Meeting report, metronomic therapy |
Pantziarka, P., Bouche, G., Sukhatme, V., Meheus, L., Rooman, I., & Sukhatme, V. P. | Author | ReDO: propranolol as an anti-cancer agent | Journal Article | Ecancermedicalscience | 2016-10-12 | Link | Link | Y | propranolol, drug repurposing, ReDO project |
Pantziarka, P., Sukhatme, V., Bouche, G., Meheus, L., & Sukhatme, V. P. | Author | ReDO: diclofenac as an anti-cancer agent | Journal Article | Ecancermedicalscience | 2016-01-11 | Link | Link | Y | drug repurposing, diclofenac, ReDO project |
Bertolini, F., Sukhatme, V.P., & Bouche, G. | Author | Patient and health systems opportunities | Journal Article | Nature Reviews Clinical Oncology | 2015-10-20 | Link | Link | N | drug repurposing, health economics |
Yolanda Augustin, Sanjeev Krishna, Devinder Kumar, Pan Pantziarka | Author | The wisdom of crowds and the repurposing of artesunate as an anticancer drug | Journal Article | Ecancermedicalscience | 2015-10-13 | Link | No link | Y | Drug repurposing, artesunate |
Vidula Sukhatme, Gauthier Bouche, Lydie Meheus, Vikas P Sukhatme and Pan Pantziark | Author | ReDO: nitroglycerin as an anti-cancer agent | Journal Article | Ecancermedicalscience | 2015-08-27 | Link | Link | Y | Nitroglycerin, drug repurposing, ReDO project |
Dinesh Chandra, Arthee Jahangir, Francois Cornelis, Klara Rombauts, Lydie Meheus, Cheryl L Jorcyk, Claudia Gravekamp | Author | Therapeutic effect of Cryoablation and Meriva in Breast Cancer | Journal Article | OncoImmunology | 2015-05-29 | Link | Link | Y | triple-negative breast cancer, cryoablation, Meriva, preclinical |
Pan Pantziarka, Vidula Sukhatme, Gauthier Bouche, Lydie Meheus and Vikas P Sukhatme | Author | ReDO: itraconazole as an anti-cancer agent | Journal Article | Ecancermedicalscience | 2015-04-15 | Link | Link | Y | Itraconazole, drug repurposing, ReDO proejct |
Rica Capistrano | Author | Phytochemical, Analytical and Preclinical Investigations on Plant Extracts as Potential Antitumoural Therapy | Thesis | 2015-03-18 | No link | Link | Y | Analytical method development, Preclinical studies, Phytochemical analysis, Plant extracts, Pancreatic cancer | |
An MT Van Nuffel, Vidula Sukhatme, Pan Pantziarka, Lydie Meheus, Vikas P Sukhatme and Gauthier Bouche | Author | ReDO: clarithromycin as an anti-cancer agent | Journal Article | Ecancermedicalscience | 2015-02-24 | Link | Link | Y | Clarithromycin, drug repurposing, ReDO project |
Pantziarka, P., Bouche, G., Meheus, L., Sukhatme, V., & Sukhatme, V.P. | Author | Repurposing in your medicine cabinet | Journal Article | Future Oncology | 2015-01-16 | Link | Link | Y | drug repurposing, health economics |
Pantziarka, P., Bouche, G., Meheus, L., Sukhatme, V., & Sukhatme, V. P. | Author | ReDO: cimetidine as an anti-cancer agent | Journal Article | Ecancermedicalscience | 2014-11-26 | Link | Link | Y | Cimetidine, drug repurposing, ReDO project |
Gauthier Bouche, Nicolas André, Shripad Banavali, Frank Berthold, Alfredo Berruti, Guido Bocci, Giovanni Brandi, Ugo Cavallaro, Saviero Cinieri, Marco Colleoni, Giuseppe Curigliano, Teresa Di Desidero, Alexandru Eniu, Nicola Fazio, Robert Kerbel, Lisa Hutchinson, Urszula Ledzewicz, Elisabetta Munzone, Eddy Pasquier, O Graciela Scharovsky, Yuval Shaked, Jaroslav Stěrba, Martin Villalba, Francesco Bertolini | Author | Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24-25 June 2014, Milan | Journal Article | Ecancermedicalscience | 2014-09-09 | Link | No link | Y | Meeting report, metronomic therapy |
Ana Ugarte, Gauthier Bouche, Lydie Meheus | Author | Inconsistencies and questionable reliability of the publication "immunotherapy of metastatic colorectal cancer with vitamin D-binding protein-derived macrophages-activating, GcMAF" by Yamamoto et al | Journal Article | Cancer Immunology, Immunotherapy | 2014-07-24 | Link | No link | Y | GcMAF |
Pantziarka, P., Bouche, G., Meheus, L., Sukhatme, V., & Sukhatme, V. P. | Author | ReDO: mebendazole as an anti-cancer agent | Journal Article | Ecancermedicalscience | 2014-07-10 | Link | No link | Y | Mebendazole, drug repurposing, ReDO project |
Pantziarka, P., Bouche, G., Meheus, L., Sukhatme, V., & Sukhatme, V. P. | Author | The Repurposing Drugs in Oncology (ReDO) Project | Journal Article | Ecancermedicalscience | 2014-07-10 | Link | Link | Y | drug repurposing, ReDO project |
Pan Pantziarka, Linda Cairns | Author | Recycling existing drugs for cancer therapy: delivering low cost cancer care | Journal Article | Ecancermedicalscience | 2014-07-10 | Link | No link | Y | Drug repurposing, health economics |
Werbrouck, J., Bouche, G., de Jonge, E., Jacomen, G., D'Hondt, V., Denys, H., Van Limbergen, E., Vandermeersch, B., De Schutter, H., Van Eycken, E., Goffin, F., & Amant, F. | Author | Evaluation of the quality of the management of cancer of the corpus uteri--selection of relevant quality indicators and implementation in Belgium. | Journal Article | Gynecologic Oncology | 2013-12-01 | Link | Link | N | EFFECT, uterine cancer |
Patrice Forget, Martine Berlière, Aline van Maanen, Francois P Duhoux, Jean-Pascal Machiels, Pierre G Coulie, Gauthier Bouche, Marc De Kock, Ketorolac in Breast Cancer trial (KBCtrial) group | Author | Perioperative ketorolac in high risk breast cancer patients. Rationale, feasibility and methodology of a prospective randomized placebo-controlled trial | Journal Article | Medical Hypotheses | 2013-08-09 | Link | No link | N | Ketorolac, trial protocol, breast cancer, drug repurposing |