Encouraging results from the AML-ViVA trial in Acute Myeloid Leukemia (AML)
Patients with Acute Myeloid Leukemia (AML) have very few treatment options when the initial chemotherapy has failed. This is particularly true for patients over 60, or with co-morbidities, who are not eligible for stem cell transplantation. On average, they will survive only a few months.
The results of the AML-ViVA trial show that low dose azacitidine, pioglitazone and all-trans retinoic acid is safe in patients who do not respond to initial chemotherapy.