Apply for funding
Do you have a cancer trial proposal that meets our 5 core criteria?
If so, don’t hesitate to apply for funding.
Our foundation supports clinical investigators in multiple ways that may include financial support if your trial meets our five criteria, has high scientific merit and is in a cancer type of our current focus (see below). We accept co-funding, can consider applications from any country and can financially support any trial phase.
We accept spontaneous applications and regularly, we run Requests for Application with a specific scope.
Spontaneous Application - How to Apply
Do not hesitate to apply for funding if you have a clinical trial proposal meeting our five core criteria in one of the following specific cancer domains:
- paediatric solid tumours, including brain tumours and sarcomas
- gynaecological cancers (excluding breast cancer)
- adult brain tumours and brain metastases
- hepatobiliary and pancreatic cancers
To assess whether your clinical trial proposal would qualify for an official submission, we need:
- a trial synopsis (max. 1 page)
- an estimation of the budget you need
- the amount and source of funding already secured for the trial
This information can be sent to firstname.lastname@example.org. We will rapidly inform you if your proposal is eligible for a full application and you will then receive a submission form to be completed.
Request for Application
In February 2022 we called out for clinical trials in brain metastases. The deadline for the letter of intent was the 1st of May 2022.
More about this call in brain metastases.
We have closed a RFA for novel treatments in pancreatic ductal adenocarcinomas (PDAC) and/or biliary tract cancer (BTC) in 2021.
More about this call for proposals in pancreatic cancer.
We have also launched a Request for Application (RFA) for clinical trials in evolutionary therapy at the end of 2020.
Our core criteria for funding
- The trial must serve patients’ interest and should be patient-centred. Applicants also need to demonstrate patient engagement in the design and execution of the trial.
- Efficacy trials need to contain Patient-Reported Outcomes Measurements.
Industry is not interested
- 2 possible situations:
- Either the intervention is off-patent or non-patentable, and no company is interested in developing and commercialising it in this specific indication.
- Or the commercial owner of the intervention (marketing authorisation holder for drugs) is not willing to provide full funding for the trial.
- In both cases, the lack of interest from companies must be justified by the applicant and confirmed by the company for on-patent products.
Improving survival or cure rate
- The ultimate goal of the intervention is to improve survival or cure rate, although not necessarily in the proposed trial.
Limited risk of trial execution failure
- The leading clinical trial team has a track record of high-quality trials – preferentially investigator-driven trials – in the field relevant to the application.
- All interventional products should be available or production should be organised.
- When multiple trials are running in the same cancer and setting, rapid changes in the treatment algorithm and fierce competition for patients may occur. This increases the risk that the trial becomes irrelevant. Fierce competition impedes accrual in non-commercial trials. We want to limit the risk of facing these issues as much as we can.
- Authorised and/or upcoming interventions in the specific cancer type and setting are limited.
- Patient participation in the proposed trial will not be impeded by other ongoing trials in the same cancer type and setting.
Our evaluation process
Every trial will be evaluated and then selected according to the same process.
1. An internal evaluation is performed by the the clinical research team of the Anticancer Fund. We will check:
- If the 5 core criteria are met.
- If the scientific rationale is sound and if contradictory data exist.
- The level of competition in terms of trials and interventions in the proposed cancer and setting (horizon scanning).
- If the budget requested is reasonable and reports other sources of funding already available.
2. If your project meets all aspects above, it is then evaluated by two external reviewers, who are specialists in the cancer concerned by the proposal, by one patient representative, and by one biostatistician.
3. Trials that are deemed excellent are then presented to our Board. In parallel, a feasibility assessment is performed.
4. The official and final decision will be made by the Board, mainly based on two questions:
- Does the trial fit within our current strategy?
- Do we have enough budget to support the trial?
Please be assured that even if we decide not to fund your trial, you will receive feedback that may increase your chances of receiving funding elsewhere. In addition, we can provide a list of other funding opportunities you may not be aware of.
Find out more about how we assist researchers here.
ACF strongly encourages Clinical Trial Transparency for the trials we support. Take a look at our Clinical Trial Transparency Policy here.
Alone we can do so little, together we can do so much.
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+32 2 268 48 16