This page is translated by Google and can contain errors. Go back to English.

A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3

A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3

Glioblastoma (GBM) is an aggressive type of brain cancer that escapes most drug treatments. Only 15-20% of patients survive more than 5 years with the usual treatment currently available (surgery, radiation, and chemotherapy using temozolomide).

In this study, a treatment regimen with 9 different drugs (CUSP9v3) in addition to low-dose, continuous temozolomide was devised to tackle this issue.

The conclusion is that CUSP9v3 can be safely administered to patients with recurrent GBM.

halatsch_2021_a_phase_ib-iia_trial_of_9_repurposed_drugs_combined_with_temozolomide_for_the_treatment_of_recurrent_glioblastoma_-_cusp9v3.pdf