Database repurposing trials in oncology
The ReDO_Trials_DB is a curated database of active clinical trials investigating the use of non-cancer drugs as potential cancer treatments. All trials in this database include one or more licensed non-cancer drugs in an intervention arm as an anticancer agent rather than for symptom control or supportive care. Primary cancer prevention trials are not included. Active trials are those which are recruiting, not yet recruiting, have temporarily paused recruitment or are following up on recruited patients. Trials which have completed, been terminated, withdrawn or with unknown status are not included.
Cite as: Pantziarka, P., Vandeborne, L., & Bouche, G. (2021). A Database of Drug Repurposing Clinical Trials in Oncology. Frontiers in Pharmacology, 10 November 2021, DOI: /10.3389/fphar.2021.790952
A machine-readable version of this database can be downloaded here: ReDO_Trials_DB.txt. The ReDO database of repurposing candidates in oncology can be accessed here: ReDO_DB.
Important note for patients! This list identifies drugs that, based on their scientific properties, warrant further scientific investigation. In most cases the existing scientific evidence for their effects on cancer is very limited. Further scientific and clinical research is needed before any statements regarding their anti-cancer activity can be made. This list is not intended to be used as a source for possible treatment options for patients.
If you need help exploring further treatment options for your situation, please take a look at our My Cancer Navigator service.
| Summary results as of last data import on: 09/12/2024 | ||
| Number of included repurposing trials | 911 | |
| Number of ReDO drugs included in trials | 186 | |
| Number of patients planned for inclusion in trials | 161601 | |
| Number of countries with Principal Investigator of trial | 44 | |
| Number | Percentage | |
| Include pediatric patients | 39 | 4.3% |
| At Phase 3 or 4 | 142 | 15.6% |
| Include control arm | 408 | 44.8% |
| Most popular drugs in trials as of last data import on: 09/12/2024 | |||
| Metformin | 128 | Celecoxib | 56 |
| Hydroxychloroquine | 40 | Acetylsalicylic Acid | 37 |
| Ascorbic acid | 35 | Propofol | 32 |
| Propranolol | 29 | Valproic Acid | 28 |
| Zoledronic Acid | 26 | Atorvastatin | 24 |
| Selumetinib | 24 | Simvastatin | 23 |
Click in header cell to sort table by that column. Hover over header cell for additional text. Click on trial row to view record.
Database build date: xx
Number of trials selected from database: xx (Filter not active)
| id | NCT Number | Title | Cancer Group | Drug | Phase |
|---|