ReDO_DB: the repurposing drugs in oncology database
Pantziarka, P., Verbaanderd, C., Sukhatme, V., Capistrano, R., Crispino, S. Gyawali, B., Rooman, I., Van Nuffel, A. MT., Meheus, L., Sukhatme, V. P., & Bouche, G. (2018). ReDO_DB: the repurposing drugs in oncology database. Ecancermedicalscience, 12, 886. https://doi.org/10.3332/ecancer.2018.886
Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described. The database has been made available as an online open-access resource (http://www.redo-project.org/db/).