Propranolol and breast cancer—a work in progress | Anticancerfund

Propranolol and breast cancer—a work in progress

PUBLICATION
Propranolol and breast cancer—a work in progress. Pantziarka, P.; Bryan, B.A.; Crispino, S.; Dickerson, E.B. Ecancermedicalscience. 2018 Jun 18. https://doi.org/10.3332/ecancer.2018.ed82.

The non-selective beta-blocker propranolol is a leading candidate for repurposing as a novel anti-cancer agent. Emerging evidence, including human data, suggests that there are multiple mechanisms of action particularly relevant to breast cancer. This editorial reviews a number of recent studies that show it has anti-metastatic activity that warrants clinical investigation, including investigation as a potential perioperative therapy in breast cancer.