No major hurdle for clinical implementation | Anticancerfund

No major hurdle for clinical implementation

We seek impact and results. We invest our resources where we believe we can make the most progress in the fight against cancer.

No major hurdle for clinical implementation

Delay between trial results and clinical use

A treatment cannot be implemented in the standard of care immediately after a clinical trial has positive results. Patients pay the price for this delay. The decision to use a new treatment in clinical practice is influenced by many non-scientific factors related to policy, cost-effectiveness, reimbursement and other economic aspects (insurance, production).

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Minimising the delay, optimising clinical implementation

The Anticancer Fund has identified three factors that are key to reducing the time between positive clinical trial results and treatment use in clinical practice. A pragmatic approach guarantees a faster clinical adoption process and the chance of bringing a new treatment option to as many patients as possible. The ACF prefers to investigate treatments that are:

  1. available on the market, ideally as a GMP-approved, marketed drug listed as an essential drug;

  2. simple, requiring minimal training and handling to keep costs low and maximise treatment compliance;

  3. affordable to patients around the world.

Our current focus areas

  • Drug repurposing

    Drug repurposing, also known as drug repositioning, is a drug development strategy predicated on the reuse of existing...
  • Less common and rare cancers

    We don’t just focus on the ‘big four’ of cancer – prostate, colon, breast and lung. We also investigate new treatment...
  • Combination therapies

    It is important to investigate the impacts of drugs beyond what they can achieve alone. Using them in combination can...
  • Preventing tumour recurrence

    For cancer survivors, the fight isn’t always over. Many are concerned about the possibility of recurrence, and living...