Projects

Here you can find a list of projects, which are financially supported by the Anticancer Fund.

An HPLC-based assay for cytochrome P450 CYP1A1 and CYP1B1

The hypothesis exists that the enzymes CYP1A1 and CYP1B1 are selectively overexpressed in several human cancers and that they are almost not present in the corresponding healthy tissue. Consequently, these enzymes could become an important tool in cancer therapy. It is on this basic concept the so called “anti-cancer activity” of salvestrols is based. Since the latter product is heavily marketed, the Anticancer Fund decided it was of prime importance to confirm or contradict the underlying assumption. Today, there is no specific assay to detect the enzymatic activity of either CYP1A1 or CYP1B1 alone.

EFFECT- EFFectiveness of Endometrial Cancer Treatments

EFFECT is a project aiming 1) to monitor the quality of the management of uterine cancer in Belgium, and 2) to compare the effectiveness of the different treatment strategies by stage.

Clinical research: Dichloroacetate (DCA)

We supported a rigorous clinical trial with DCA in order to know if it could be safely given to patients with glioblastoma.

Verelst Uterine Cancer Fund (closed subproject)

Development of immunotherapy for endometrial cancer.

Synchronization of chemotherapy to the anti-tumor immune cycle

A professional clinical research organization was not able to confirm the presence of immune oscillations based on CRP or effector or regulatory T cells and published these results.