Gestational trophoblastic disease

Introduction

This information is produced and provided by the National Cancer Institute (NCI). We only provide general information and advice from medical professionals should be followed. More information is available on the NCI-website at www.cancer.gov. This information was last updated by NCI in July 2014.

 

Any of a group of tumors that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta) after fertilization of an egg by a sperm. The two main types of gestational trophoblastic diseases are hydatidiform mole and choriocarcinoma. Also called gestational trophoblastic tumor.

 

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Synonyms

Gestational trophoblastic disease

Gestational trophoblastic tumor

Hydatidiform mole

Choriocarcinoma

Invasive mole

Placental site trophoblastic tumour

Epithelioid trophoblastic tumour

Clinical trials

A clinical trial is a research study conducted with patients to evaluate whether a new treatment is safe (safety) and whether it works (efficacy). Clinical trials are performed to test the efficacy of drugs but also non-drug treatments such as radiotherapy or surgery and combinations of different treatments. Clinical trials take place in all kinds of hospitals and clinics, but mostly in academic hospitals. They are organized by researchers and doctors.

The Anticancer Fund provides a tool to search for phase III clinical trials by type of cancer and by country. For Belgium, the Netherlands, Switzerland, Luxembourg, France and the UK, the Anticancer Fund provides contacts to get more information about the phase III clinical trials currently ongoing. Discuss the possibilities of participating in one of these clinical trials with your doctor.

The list of the phase III clinical trials for gestational trophoblastic diseases is available here.